At INC Research, we understand that cancer is not one disease, but a category of widely varying diseases, each with its own specialized scientific complexities, patient populations and range of treatment options. Our Oncology and Hematology practice is dedicated to the execution of clinical trials in these complex indications and is staffed by dedicated professionals with backgrounds in oncology drug development in academia, industry and CRO settings. This expertise, combined with INC Research’s Trusted Process® methodology for delivering dependable trial outcomes, provides the resources, clinical expertise and development know-how to help our clients with every facet of their Oncology research.
Wide-ranging Expertise
The oncology research community is engaged in an intense quest for new and better therapeutic options. We are passionately committed to this quest. INC Research has global teams dedicated to the development, implementation and execution of a broad variety of oncology research programs.
- Our Oncology Practice is led by industry experienced oncology drug developers with specialist understanding of Early Phase development, Hematology and Solid Tumor based oncology trials.
- All of our project teams have substantial, relevant and current experience in the unique complexities of Oncology research and are dedicated to this Therapeutic specialty.
- We have managed Phase I-IV trials spanning a full spectrum of therapies, geographies, endpoints and indications.
- We offer services from protocol development through data analysis and completion of the final study report.
- Our proven, proactive recruitment methods speed enrollment and aid retention.
- We provide agency-experienced regulatory consultation for oncology research in a variety of regulatory climates.
Structured for Success
Early Phase Development
INC Research recognizes that Oncology research has a particular structure through which all trials progress and has made structural commitments to facilitate specialization in this process. INC Research has a specialized Phase I/II delivery group focused solely in Oncology within which all Early Phase development efforts are executed. This focus enables our customers to bring smaller, earlier phase projects to INC Research and be comfortable in the knowledge that their trial will be highly visible within INC Research, will be executed at the most appropriate research centers and will garner the appropriate levels of management oversight to ensure successful execution.
Hematology
INC Research also provides expertise specifically focused on the development of Hematological products for both Hematology and Hem Onc indications. This specialist group contains Hematologists positioned strategically around the world along with clinical development executives and project teams with extensive experience in the delivery of hematology research. The hematology networks and investigative sites around the globe bring a specialist set of requirements and INC Research has created a team to continually focus on developing the best project based solutions for our customers; thus enabling the correct placement of trials in the right countries and investigative sites to facilitate rapid and appropriate enrollment.
Robust Investigator Relationships
Because oncology is such a rapid-moving and competitive field, we know that gaining access to the right investigators for an oncology study involves much more than simply keeping a database. INC Research has strong relationships with key opinion leaders, providing access to an extensive global network of leading oncologists. We’ve also developed good partnerships with cooperative groups such as the Eastern Oncology Group in the United States, the Clinical Oncological Society of Australia and the Grupo Oncologico Cooperativo del Sur in Latin America, and use them as excellent sources of expertise for our studies. These relationships ensure we get the very best and most up-to-date advice from the outset of any study, helping to save you resources in the long term.
Our ability to build strong investigator relationships to drive study enrollment has been consistently recognized. We are the only CRO to have been ranked among the top three providers in five consecutive years by CenterWatch surveys of U.S. and European investigative sites.1
Global Reach, Individualized Solutions
Our expertise in oncology is spread strategically throughout key countries, with critical knowledge of regional regulatory, medical and cultural nuances.
- In Asia/Pacific, we have offices in India, where there are 800,000 new cancer cases every year and oncology is the most researched therapeutic area.2
- In Australia we have expert oncology staff. This is a desirable location for conducting Phase I-IV oncology trials, particularly in the areas of breast cancer and melanoma.
- In Latin America, we have significant experience in gastric and hepatic cancers as well as cervical cancer, which is less prevalent in developed countries due to high rates of screening.
INC Research Oncology Expertise
- Actinic keratoses
- Acute lymphoblastic leukemia
- Acute myelocytic leukemia
- Anaplastic large cell lymphoma
- Astrocytoma
- B-cell lymphoma
- Basal cell carcinoma
- Bladder cancer
- Bone cancer
- Bowen’s disease
- Brain cancer
- Breast cancer
- Cancer-induced cachexia
- Cancer pain
- Carcinoid syndrome
- Cervical cancer
- Chronic lymphocytic leukemia
- Chronic myelogenous leukemia
- Chemotherapy-induced:
- Anemia
- Diarrhea
- Mucositis
- Nausea and vomiting
- Neuropathy
- Neutropenia
- Colorectal cancer
- Familial adenomatous polyposis
- Gastrointestinal cancer
- Glioblastoma
- Glioma
- Head and neck cancer
- Hepatocellular cancer
- Hodgkin’s lymphoma
- Leukemia
- Lymphoma
- Mantel cell lymphoma
- Medulloblastoma
- Melanoma
- Multiple myeloma
- Myelodysplastic syndrome
- Non-Hodgkin’s lymphoma
- Non-small cell lung cancer
- Oral cancers
- Osteosarcoma
- Ovarian cancer
- Pancreatic cancer
- Prostate cancer
- Radiation-induced:
- Esophagitis
- Mucositis
- Nausea and vomiting
- Pneumonitis
- Renal cell carcinoma
- Sarcoma
- Skin cancer prevention
- Small cell lung cancer
- Soft tissue sarcoma
- Solid tumors
- Sporadic adenomatous polyposis
- Testicular cancer
- Thrombocythemia
- Thyroid cancer
- Tumorlysis syndrome
- Uterine cancer
- Vulva carcinoma
For more information on INC Research’s therapeutic expertise in Oncology, click here.
Reference
1. CenterWatch Investigative Site Surveys, 2007–2010.
2. Cherian Varghese, Cancer Prevention and Control in India. Available at: www.whoindia.org/linkfiles/cancer_resource_pg56to67.pdf |
Case Studies
Oncology: From Preferred Provider to Strategic Partner
Oncology: Turning Around a Large Combination Study
Oncology: Prostate Cancer Study
Oncology: Innovation in Phase I Studies
Oncology: Phase IIIb Global Study
Oncology: Phase II Hematology Study
Leadership
Alistair Macdonald
General Manager & EVP, Oncology
Nicholas Kenny, PhD
Executive Vice President, Oncology
Chris Smyth, PhD, MBA
Senior Vice President, Oncology
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